ANG Wee Han

 

ANG Wee Han

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B.Sc.(Hons), Imperial College London (1992-1995)

Ph.D., École Polytechnique Fédérale de Lausanne (2003-2007)

Postdoc, Massachusetts Institute of Technology (2007-2009)


E-mail: chmawh@nus.edu.sg

Website: http://weehan.sgresearcher.net/ 


Research Interests



Representative Publications

1. F. Chin, S. Q. Yap, J. Li, G. Pastorin*, W. H. Ang*, Ratiometric delivery of cisplatin and doxorubicin using tumour-targeting carbon-nanotubes entrapping platinum(IV) prodrugs, Chem. Sci., 2014, in press

2. L. Yoong, B. S. Wong, Q. L. Zhou, C. F. Chin, J. Li, T. Venkatesan, H. K. Ho, V. Yu, W. H. Ang*, G. Pastorin*, Enhanced cytotoxicity to cancer cells by mitochondria-targeting MWCNTs containing platinum(IV) prodrug of cisplatin, Biomaterials, 2014, 35, 748-753

3. Montagner, S. Q. Yap, W. H. Ang*, A fluorescent probe for investigating the activation of anticancer platinum(IV) prodrugs based on the cisplatin scaffold, Angew. Chem. Int. Ed., 2013, 52, 11785-11789

4. Paira, M. J. Chow, G. Venkatesan, V. K. Kosaraju, S. L. Cheong, K.-N. Klotz, W. H. Ang*, G. Pastorin*, Organoruthenium antagonists of human A3 adenosine receptors, Chem. Eur. J., 2013, 19, 8321-8330

5. F. Chin, Q. Tian, M. I. Setyawati, W. Fang, E. S. Q. Tan, D. T. Leong, W. H. Ang*, Tuning the activity of platinum(IV) anticancer complexes through asymmetric acylation, J. Med. Chem., 2012, 55, 7571-7582

6. Li, S. Q. Yap, C. F. Chin, G. Pastorin*, W. H. Ang*, Platinum(IV) prodrugs entrapped within multiwalled carbon nanotubes: Selective release by chemical reduction and hydrophobicity reversal, Chem. Sci., 2012, 3, 2083-2087

7. X. Ong, C. W. Yap, W. H. Ang*, Rational Design of Selective organoruthenium inhibitors of protein tyrosine phosphatase 1B, Inorg. Chem., 2012, 51, 12483-12492

8. Tian, W. Wong, Y. Xu, Y. Chan, H. K. Ho, G. Pastorin, W. H. Ang*, Immobilisation of quantum dots by bio-orthogonal PCR amplification and labelling for direct gene detection and quantitation, Chem. Commun., 2012, 48, 5467-5469

9. Y. Q. Wong, J. Y. Lau, W. H. Ang*, Harnessing chemoselective imine ligation for tethering bioactive molecules to platinum(IV) prodrugs, Dalton Trans., 2012, 41, 6104-6111

10. Y. Q. Tan, P. J. Dyson, W. H. Ang*, Acetal-Functionalized RAPTA Complexes for Conjugation and Labeling, Organometallics, 2011, 30, 5965-5971




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