教育背景
1987—1991 复旦大学高分子系,学士
1995—2000 加拿大麦吉尔大学化学系,博士
工作经历
2003—2010 新加坡国立大学化学系,助理教授
2010—2014 新加坡国立大学化学系,副教授
2014—至今 新加坡国立大学化学系,教授
2016—至今 新加坡国立大学苏州研究院,首席研究员研究领域
1. 有机小分子催化的不对称反应
2. 过渡金属催化的高选择性不对称反应
3. 以绿色化学为导向的新反应方法和技术
代表性论文(>150 文章,>7,200 引用, H-Index 52)
[1] Bai, X.; Wu, C.; Ge, S.; Lu, Y. “Pd/Cu-Catalyzed
Enantioselective Sequential Heck-Sonogashira Coupling: Asymmetric Synthesis of
Oxindoles Containing Trifluoromethylated Quaternary Stereogenic Centers Centers”, Angew. Chem. Int. Ed., 2020, 59, 2764.
[2] Mei, G.-J.; Tang, X.; Tasdan, Y.; Lu, Y. “Enantioselective
Dearomatization of Indoles by an Azoalkene-Enabled (3+2) Reaction: Access to
Pyrroloindolines”, Angew. Chem. Int. Ed. 2020, 58,
648.
[3] Wu, M.; Han, Z.; Li, K.; Wu, J.; Ding, K. Lu, Y. “Cyclohexyl-Fused, Spirobiindane-derived, Phosphine-catalyzed Synthesis of
Tricyclic γ-Lactams and Kinetic Resolution of γ-Substituted Allenoates”, J.
Am. Chem. Soc., 2019, 141,
16362.
[4] Chan, W.-L.; Tang, X.; Zhang, F.; Quek, G.; Mei,
G.-J.; Lu, Y. “Phosphine-Catalyzed (3+2) Annulation of Isoindigos with
Allenes: Enantioselective Formation of Two Vicinal Quaternary Stereogenic
Centers”, Angew. Chem. Int. Ed. 2019, 58, 6260。
[5] Li, K.; Gonçalves, T. P.; Huang, K.-W.; Lu, Y. “Dearomatization
of 3-Nitroindoles by a Phosphine-catalyzed Enantioselective [3+2] Annulation
Reaction”, Angew. Chem. Int. Ed. 2019, 58, 5427.
[6] Ni, H.; Chan, W.-L.; Lu, Y. “Phosphine-catalyzed
Asymmetric Organic Reactions”, Chem. Rev. 2018, 118, 9344.
[7] Ni, H.; Tang, X.; Zheng, W.; Yao, W.; Ullah, N.; Lu, Y. “Enantioselective
Phosphine-Catalyzed Formal [4+4] Annulation of a,b-Unsaturated
Imines and Allene Ketones: Construction of Eight-membered Rings”, Angew.
Chem. Int. Ed. 2017, 56, 14222.
[8] Yao, W.; Dou, X.; Wen, S.; Wu, J.; Vittal, J. J.; Lu, Y. “Enantioselective
Desymmetrization of Cyclohexadienones via an Intramolecular Rauhut–Currier
Reaction of Allenoates”, Nat. Commun. 2016, 7, 13024.
[9] Wang, T.; Han, X.; Zhong, F.; Yao, W.; Lu, Y. “Amino
Acid-derived Bifunctional Phosphines for Enantioselective Transformations”, Acc.
Chem. Res. 2016, 49, 1369.